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Silva Fredduzzi Selected Research

Mental Disorders (Mental Disorder)

7/2009Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression.
4/2005The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles.

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Silva Fredduzzi Research Topics

Disease

4Parkinson Disease (Parkinson's Disease)
07/2009 - 02/2002
3Neuralgia (Stump Neuralgia)
02/2012 - 02/2005
3Chronic Pain
11/2007 - 02/2005
3Pain (Aches)
11/2007 - 02/2005
3Hyperalgesia
04/2005 - 10/2003
2Mental Disorders (Mental Disorder)
07/2009 - 04/2005
2Dyskinesias (Dyskinesia)
07/2009 - 12/2003
1Movement Disorders (Movement Disorder)
07/2009
1Catalepsy
02/2009
1Nervous System Diseases (Neurological Disorders)
11/2007

Drug/Important Bio-Agent (IBA)

3metabotropic glutamate receptor type 1IBA
02/2012 - 04/2005
3Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
07/2009 - 12/2003
2Levodopa (L Dopa)FDA LinkGeneric
07/2009 - 02/2002
22- (2- furanyl)- 7- (2- (4- (4- (2- methoxyethoxy)phenyl)- 1- piperazinyl)ethyl)- 7H- pyrazolo(4,3- e)(1,2,4)triazolo(1,5- c)pyrimidine- 5- amineIBA
07/2009 - 02/2009
2Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
11/2007 - 04/2005
1(7- (2- (4- difluorophenyl)- 1- piperazinyl)ethyl)- 2- (2- furanyl)- 7H- pyrazolo(4,3- e)(1,2,4)triazolo(1,5- c)pyrimidin- 5- amineIBA
07/2009
1AminesIBA
07/2009
1pyrimidineIBA
02/2009
1Haloperidol (Haldol)FDA LinkGeneric
02/2009
1PyrimidinesIBA
02/2009
1(4- methoxy- phenyl)- (6- methoxy- quinazolin- 4- yl)- amine HClIBA
04/2005
1Formaldehyde (Formol)FDA Link
04/2005
1pyridineIBA
04/2005
16-methyl-2-(phenylethynyl)pyridineIBA
04/2005
1Anti-Anxiety Agents (Anxiolytics)IBA
04/2005
1Agouti-Related ProteinIBA
02/2005
1salicylhydroxamic acid (SHAM)IBA
02/2005
1Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
02/2005
1MelanocortinsIBA
02/2005
1Dopamine (Intropin)FDA LinkGeneric
12/2003
1Neuroprotective AgentsIBA
12/2003
1Pro-Opiomelanocortin (Proopiomelanocortin)IBA
10/2003

Therapy/Procedure

3Ligation
11/2007 - 02/2005
1Spinal Injections
02/2005
1Therapeutics
12/2003